Evidence · Systematic review or meta-analysis
Probiotic supplementation in preterm infants does not affect the risk of retinopathy of prematurity: a meta-analysis of randomized controlled trials.
- Enteral feeding
- Eyes and hearing
- Infection
- Infection prevention
- Late-onset sepsis
- Medical
- Nursing
- Nutrition and gastrointestinal
- Retinopathy of prematurity
This paper is from 2017, more than five years ago. Newer evidence may have been published since.
Summary
This systematic review and meta-analysis of eleven randomised controlled trials (4250 preterm infants) examined whether probiotic supplementation alters the risk of retinopathy of prematurity. Probiotics were associated with a reduced rate of late-onset sepsis, but no significant effect was found on any-stage or severe ROP. Meta-regression showed no association between reduction in sepsis and severe ROP risk. The authors conclude that infection prevention by probiotics does not appear to influence ROP development in preterm infants.
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- Licence:
- Open (Creative Commons)
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