Evidence · Systematic review or meta-analysis
Probiotics Prevent Late-Onset Sepsis in Human Milk-Fed, Very Low Birth Weight Preterm Infants: Systematic Review and Meta-Analysis.
- Allied health
- Breast milk and breastfeeding
- Enteral feeding
- Infection
- Late-onset sepsis
- Medical
- Necrotising enterocolitis
- Nursing
- Nutrition and gastrointestinal
This paper is from 2017, more than five years ago. Newer evidence may have been published since.
Summary
Systematic review and meta-analysis of randomised controlled trials of probiotic supplementation in preterm and very low birth weight infants, examining late-onset sepsis prevention according to feeding type (exclusive human milk versus formula or mixed feeding). Twenty-five studies were included in the meta-analysis. Overall, probiotics were associated with a lower incidence of late-onset sepsis, with benefit seen in exclusively human milk-fed infants. The authors call for further work on the interplay between probiotics, human milk and feeding practices.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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