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Evidence · Randomised trial

Effect of a Multi-Strain Probiotic on Growth and Time to Reach Full Feeds in Preterm Neonates.

Randomised trialNutrients2022Full text
  • Allied health
  • Enteral feeding
  • Growth
  • Medical
  • Necrotising enterocolitis
  • Nursing
  • Nutrition and gastrointestinal

Summary

Double-blind, placebo-controlled randomised trial of a named multi-strain probiotic (Labinic) given daily for 28 days to preterm neonates. It reports time to reach full enteral feeds, time to regain birthweight and growth measures including weight, length, head circumference and weight Z-scores. The probiotic group reached full feeds earlier and showed greater weight gain from day 21 onwards. The authors frame probiotics as a low-cost intervention to reduce postnatal growth restriction in very and extremely low birth weight infants.

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