Evidence · Systematic review or meta-analysis
Burden of severe neonatal jaundice: a systematic review and meta-analysis.
- Anaemia and transfusion
- Jaundice and haematology
- Jaundice and phototherapy
- Medical
- Nursing
This paper is from 2017, more than five years ago. Newer evidence may have been published since.
Summary
Systematic review and meta-analysis estimating the global burden of severe neonatal jaundice across WHO regions, defined by acute bilirubin encephalopathy/kernicterus, exchange transfusion or jaundice-related death. Population-based studies from 1990 to 2017 were pooled using random effects models and meta-regression. Few population-based studies exist, most from high-income countries, yet the incidence of severe jaundice and exchange transfusion is markedly higher in the African and Southeast Asian regions. It highlights the substantial burden in low- and middle-income countries and the need for better detection and management.
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- Licence:
- Open (Creative Commons)
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