Evidence · Randomised trial
The efficacy and safety of peripheral intravenous parenteral nutrition vs 10% glucose in preterm infants born 30 to 33 weeks' gestation: a randomised controlled trial.
- Allied health
- Comfort and nursing care
- Fluids and electrolytes
- Growth
- Line and device care
- Medical
- Nursing
- Nutrition and gastrointestinal
- Parenteral nutrition
This paper is from 2020, more than five years ago. Newer evidence may have been published since.
Summary
Single-centre randomised controlled trial in 92 preterm infants born 30 to 33 weeks' gestation comparing low-osmolarity peripheral intravenous parenteral nutrition with peripheral 10% glucose started within 24 hours of birth. Peripheral parenteral nutrition increased the rate of weight gain to 21 days and to discharge, shortened time to regain birthweight and improved length gain. Safety outcomes included one rapidly resolving extravasation and transiently higher urea and triglyceride levels without abnormal values. It informs choice of intravenous nutrition route and type for moderately preterm infants expected to reach full feeds quickly.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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