Evidence · Systematic review or meta-analysis
Probiotics to prevent necrotizing enterocolitis and reduce mortality in neonates: A meta-analysis.
- Enteral feeding
- Medical
- Necrotising enterocolitis
- Neonatal transport
- Nursing
- Nutrition and gastrointestinal
- Transport
Summary
An updated meta-analysis of 70 studies evaluating the efficacy and safety of prophylactic probiotic supplementation in neonates for preventing necrotising enterocolitis. Databases including PubMed, Embase, Scopus, Web of Science and CNKI were searched to December 2021, with pooled random-effects risk ratios. The authors report that probiotics significantly reduced the incidence of stage II or greater NEC and mortality. Relevant to clinicians considering probiotic policies for preterm infants.
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- Open (Creative Commons)
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