Evidence · Systematic review or meta-analysis
Prevalence of Bacteremia and Bacterial Meningitis in Febrile Neonates and Infants in the Second Month of Life: A Systematic Review and Meta-analysis.
- Early-onset sepsis
- Infection
- Late-onset sepsis
- Medical
This paper is from 2019, more than five years ago. Newer evidence may have been published since.
Summary
This systematic review and meta-analysis of 12 studies (over 15,000 culture results) estimates the prevalence of bacteraemia and bacterial meningitis in febrile neonates and infants in their second month of life presenting to ambulatory settings after 1990. Febrile neonates had roughly twice the rate of bacteraemia and meningitis compared with older infants, including in the era of group B Streptococcus intrapartum prophylaxis. It is relevant to clinicians assessing febrile infants presenting from the community, such as in emergency departments or on readmission.
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- Licence:
- Open (Creative Commons)
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