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Evidence · Systematic review or meta-analysis

Selenium deficiency and the effects of supplementation on preterm infants.

Systematic review or meta-analysisRevista Paulista de Pediatria2014Over 5 years oldFull text
  • Allied health
  • Breast milk and breastfeeding
  • Bronchopulmonary dysplasia
  • Enteral feeding
  • Medical
  • Nutrition and gastrointestinal
  • Parenteral nutrition
  • Respiratory

This paper is from 2014, more than five years ago. Newer evidence may have been published since.

Summary

This systematic review examines blood selenium concentrations in preterm infants in relation to gestational age, feeding type, supplementation and clinical outcomes. It reports that preterm and low birth weight infants have lower selenium levels, and that low selenium is associated with increased risk of respiratory disease. Deficiency is also linked to formula, enteral and parenteral nutrition. The optimal dose and duration of supplementation remain uncertain, although supplementation appears to reduce complications of prematurity.

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