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Evidence · Randomised trial

Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation.

Randomised trialArchives of Disease in Childhood: Fetal and Neonatal Edition2018Over 5 years oldFull text
  • Families and professional practice
  • Family-integrated care
  • Intraventricular haemorrhage and white matter injury
  • Medical
  • Neurodevelopmental follow-up
  • Neurology
  • Wellbeing

This paper is from 2018, more than five years ago. Newer evidence may have been published since.

Summary

Randomised trial of 511 infants born before 33 weeks' gestation across 14 London hospitals comparing disclosure of term-equivalent MRI results with cranial ultrasound results. The primary outcome was maternal anxiety, with secondary outcomes including prediction of neurodevelopment at 20 months, health-related quality of life and costs. MRI was associated with a slightly greater fall in maternal anxiety and modestly better prediction of motor impairment, but at higher cost per infant. The authors conclude that routine MRI provides only modest benefits.

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