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Evidence · Systematic review or meta-analysis

Outcomes of endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid: a systematic review and meta-analysis.

Systematic review or meta-analysisArchives of Disease in Childhood: Fetal and Neonatal Edition2021Full text
  • Cardiovascular
  • Delivery room and stabilisation
  • Meconium aspiration
  • Medical
  • Newborn life support
  • Nursing
  • Persistent pulmonary hypertension
  • Pneumothorax and air leak
  • Respiratory

Summary

This systematic review and meta-analysis of randomised controlled trials compares endotracheal suctioning with no endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid. Four trials including 581 infants were analysed, with meconium aspiration syndrome as the primary outcome and respiratory, resuscitation and other neonatal outcomes as secondary measures. No significant difference in meconium aspiration syndrome was found, suggesting routine early endotracheal suctioning may not alter neonatal outcomes. It is relevant to delivery room resuscitation practice for non-vigorous meconium-stained infants.

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